(AP) - A look at the diabetes drugs under investigation by the U.S. Food and Drug Administration over possible risks of pancreas inflammation and cellular changes in the pancreas that occur before cancer.
DRUG CLASS: GLP-1 mimickers, taken by nearly 1 million Americans.
HOW THEY WORK: Injections needed anywhere from twice a day to once a week, they make the body produce more insulin to lower blood sugar.
MAKER: Bristol-Myers Squibb Co.
CHEMICAL/BRAND NAMES: exenatide/Byetta and Bydureon
MAKER: Novo Nordisk A/S:
CHEMICAL/BRAND NAMES: liraglutide/Victoza
DRUG CLASS: DPP-4 inhibitors, taken by about 1.6 million Americans.
HOW THEY WORK: Pills taken once or twice a day, they stimulate insulin production and limit release of a hormone that raises blood sugar levels.
MAKER: Merck & Co.
CHEMICAL/BRAND NAMES: sitagliptin/Januvia, Janumet, Janumet XR, Juvisync
MAKER: Bristol-Myers Squibb Co. & AstraZeneca PLC
CHEMICAL/BRAND NAMES: saxagliptin/Onglyza and Kombiglyze
MAKER: Eli Lilly and Co. and Boehringer Ingelheim Pharmaceuticals Inc.
CHEMICAL/BRAND NAMES: linagliptin/Jentadueto and Tradjenta
MAKER: Takeda Pharmaceuticals Co. Ltd.
CHEMICAL/BRAND NAMES: alogliptin/Nesina, Kazano and Oseni
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GREENWICH, Conn. (AP) — A multi-vehicle crash closed part of Interstate 95 in southwestern Connecticut for about two hours as road conditions turned slippery with the arrival of a wintry storm.
Lawmakers in Connecticut and New York are calling on the Federal Railroad Administration to take immediate action to try and prevent another deadly train crash like the one that happened last weekend in New York City.
Members of the Machinists union who work at jet-engine maker Pratt & Whitney have approved a new three-year contract.
Manchester police are investigating what lead one man to allegedly kill three women and then take his own life.
The University of Connecticut has awarded the first two scholarships under a program launched to help those affected by last year's massacre at the Sandy Hook Elementary School in Newtown.
A student accused of setting off a lockdown and massive police response at Central Connecticut State University by wearing a ninja-like costume on campus is set to face a judge for the first time.
Newtown police officers rescued two people from a house fire, early Sunday.
Enfield resident Harold Slater was just 20-years-old the day he witnessed the bombing of Pearl Harbor.
Two men were arrested after breaking into a home then driving at officers during a pursuit in Waterbury on Saturday night.
HARTFORD, Conn. (AP) — Connecticut's governor is calling for houses of worship to mark the first anniversary of the Newtown school shooting by ringing their bells 26 times — once for each of the victims killed inside Sandy Hook Elementary …