J&J: Booster dose of its COVID shot prompts strong response


LONDON (AP/WTNH) — Johnson & Johnson released data showing that a booster dose to its one-shot coronavirus vaccine provides a strong immune response months after people receive the first dose.

J&J said in a statement Tuesday that it ran two early studies in people previously given its vaccine and found that a second dose produced an increased antibody response in adults from age 18 to 55. The study’s results haven’t yet been peer-reviewed.

“A booster dose of the Johnson & Johnson COVID-19 vaccine further increases antibody responses among study participants who had previously received our vaccine,” said Dr. Mathai Mammen, global head of research and development at J&J.

The company is in talks with regulators including the U.S. Food and Drug Administration, the European Medicines Agency, and others regarding using booster doses of its vaccine.

Yale School of Medicine Infectious Disease Doctor Albert Shaw spoke to News 8 about the newly released data.

“A second shot with the Johnson & Johnson vaccine was able to induce very high levels of protective antibodies and in a very short follow-up period was highly protective against severe outcomes from COVID-19,” Dr. Shaw said.

Dr. Shaw says while the research is preliminary, it is reassuring that the booster dose is able to increase antibody levels, which he says are an important parameter of protection.

The research revealed two doses of the Johnson & Johnson vaccine provide 94% protection from COVID infection, comparable to the two regular doses of Pfizer and Moderna.

The results will need FDA and CDC review of the entire presentation. Who will need booster vaccines is still to be determined.

Copyright 2021 Nexstar Media Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

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