Scientists think that the high-fat diet the mice were eating led to overgrowth of bad gut bacteria, which leads to inflammation.
This inflammation can cause joint damage.
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When the mice were fed pre-biotics to promote good gut bacteria, they were still overweight, but their joints were protected from damage.
Remember, this study was done in mice, so we can’t recommend you start taking probiotics for your joints just yet.
Simple lifestyle changes, like eating right and exercising regularly, are always a good choice.