According to police, on Tuesday around 12 noon, officials served a narcotics-related warrant at a residence on Vauxhall Street.
Officials say they located and seized crack cocaine, drug paraphernalia, digital scales and other items inside of the residence.
Police then arrested 37-year-old Kerry Barnum and 29-year-old Daniel Hunt, both of New London.
Barnum faces multiple charges, including possession of narcotics and operating a drug factory.
Hunt, a previously convicted felon, has been charged with possession of drug paraphernalia and criminal possession of ammunition.